The Conflict between Regulatory Agencies over the 20,000-Fold Lowering of the Tolerable Daily Intake (TDI) for Bisphenol A (BPA) by the European Food Safety Authority (EFSA)
Frederick S Vom Saal
(1)
,
Michael Antoniou
(2)
,
Scott M Belcher
(3)
,
Ake Bergman
(4)
,
Ramji K Bhandari
(1)
,
Linda S Birnbaum
(5)
,
Aly Cohen
(6)
,
Terrence J Collins
(7)
,
Barbara Demeneix
(8)
,
Anne Marie Fine
(9)
,
Jodi A Flaws
(10)
,
Veronique Gayrard
(11)
,
William H Goodson
(12)
,
Andrea C Gore
(13)
,
Jerrold J Heindel
(3)
,
Patricia A Hunt
(14)
,
Taisen Iguchi
(15)
,
Christopher D Kassotis
(16)
,
Andreas Kortenkamp
(17)
,
Robin Mesnage
(18)
,
Jane Muncke
(19)
,
John Peterson Myers
(20)
,
Angel Nadal
(21)
,
Retha R Newbold
(22)
,
Vasantha Padmanabhan
(23)
,
Paola Palanza
(24)
,
Zandra Palma
,
Stefano Parmigiani
(24)
,
Lyn Patrick
,
Gail S Prins
(25)
,
Cheryl S Rosenfeld
(26)
,
Niels E Skakkebaek
(27)
,
Carlos Sonnenschein
(28)
,
Ana M Soto
(28)
,
Shanna H Swan
(29)
,
Julia A Taylor
(1)
,
Pierre-Louis Toutain
(30)
,
Frank A von Hippel
(31)
,
Wade V Welshons
(1)
,
Daniel Zalko
(11)
,
R. Thomas Zoeller
(32)
1
Mizzou -
University of Missouri [Columbia]
2 King's College London, School of Medicine
3 NC State - North Carolina State University [Raleigh]
4 Stockholm University
5 NIEHS-NIH - National Institute of Environmental Health Sciences [Durham, NC, USA]
6 Integrative Rheumatology Associates
7 CMU - Carnegie Mellon University [Pittsburgh]
8 PhyMA - Physiologie moléculaire et adaptation
9 Environmental Medicine Education International
10 UIUC - University of Illinois at Urbana-Champaign [Urbana]
11 ToxAlim - ToxAlim
12 California Pacific Medical Center Research Institute
13 University of Texas at Austin [Austin]
14 WSU - Washington State University
15 YCU - Yokohama City University
16 Wayne State University [Detroit]
17 Brunel University London [Uxbridge]
18 King's College London School of Medicine, King's College Hospital
19 FOOD PACKAGING FORUM FOUNDATION ZURICH CHE
20 Environmental Health Sciences
21 UMH - Universidad Miguel Hernández [Elche]
22 NIEHS, National Institutes of Health, Research Triangle Park, NC 27709, USA
23 University of Michigan [Ann Arbor]
24 UNIPR - Università degli studi di Parma = University of Parma
25 UIC - University of Illinois [Chicago]
26 Thompson Center for Autism and Neurobehavioral Disorders
27 ITU - IT University of Copenhagen
28 Tufts University School of Medicine [Boston]
29 MSSM - Icahn School of Medicine at Mount Sinai [New York]
30 InTheRes - Innovations Thérapeutiques et Résistances
31 University of Arizona
32 UMass Amherst - University of Massachusetts [Amherst]
2 King's College London, School of Medicine
3 NC State - North Carolina State University [Raleigh]
4 Stockholm University
5 NIEHS-NIH - National Institute of Environmental Health Sciences [Durham, NC, USA]
6 Integrative Rheumatology Associates
7 CMU - Carnegie Mellon University [Pittsburgh]
8 PhyMA - Physiologie moléculaire et adaptation
9 Environmental Medicine Education International
10 UIUC - University of Illinois at Urbana-Champaign [Urbana]
11 ToxAlim - ToxAlim
12 California Pacific Medical Center Research Institute
13 University of Texas at Austin [Austin]
14 WSU - Washington State University
15 YCU - Yokohama City University
16 Wayne State University [Detroit]
17 Brunel University London [Uxbridge]
18 King's College London School of Medicine, King's College Hospital
19 FOOD PACKAGING FORUM FOUNDATION ZURICH CHE
20 Environmental Health Sciences
21 UMH - Universidad Miguel Hernández [Elche]
22 NIEHS, National Institutes of Health, Research Triangle Park, NC 27709, USA
23 University of Michigan [Ann Arbor]
24 UNIPR - Università degli studi di Parma = University of Parma
25 UIC - University of Illinois [Chicago]
26 Thompson Center for Autism and Neurobehavioral Disorders
27 ITU - IT University of Copenhagen
28 Tufts University School of Medicine [Boston]
29 MSSM - Icahn School of Medicine at Mount Sinai [New York]
30 InTheRes - Innovations Thérapeutiques et Résistances
31 University of Arizona
32 UMass Amherst - University of Massachusetts [Amherst]
Frederick S Vom Saal
- Fonction : Auteur
- PersonId : 1417761
- ORCID : 0000-0002-0488-3264
Zandra Palma
- Fonction : Auteur
Lyn Patrick
- Fonction : Auteur
Résumé
The European Food Safety Authority (EFSA) recommended lowering their estimated tolerable daily intake (TDI) for bisphenol A (BPA) 20,000-fold to 0:2 ng=kg body weight ðBWÞ=day. BPA is an extensively studied high production volume endocrine disrupting chemical (EDC) associated with a vast array of diseases. Prior risk assessments of BPA by EFSA as well as the US Food and Drug Administration (FDA) have relied on industry-funded studies conducted under good laboratory practice protocols (GLP) requiring guideline end points and detailed record keeping,
Domaines
Médecine humaine et pathologie
Fichier principal
2024_saal-Environmental Health Perspectives.pdf (306.42 Ko)
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